Kartheiser was born in Minneapolis, Minnesota, the son of Janet Marie (née Gruyé), who ran a nursery, and James Ralph Kartheiser, who sold construction equipment.\n', '

The youngest of six children, he has four sisters, Andrea, Colette, Elise and Theresa, and a brother, Nathan. Kartheiser attended Apple Valley High School in Apple Valley, Minnesota. He is of German, and to an extent Polish, Finnish, and Swedish ancestry.\n', '

Some of Kartheiser\'s first acting experiences were on stage of Children\'s Theatre Company in Minneapolis, including roles in Pippi Longstocking, Our Town, Dr. Seuss\' The 500 Hats of Bartholomew Cubbins, and Rebecca of Sunnybrook Farm.\n', '

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