Landau was born in Los Angeles to actor parents Martin Landau and Barbara Bain. Both her parents were Jewish. Her older sister is film producer Susan Landau Finch. She spent her early childhood in West Los Angeles. Landau is a former professional ballerina.
Landau has made some independent films such as Where The Road Runs Out, Fairfield, Monster Mutt, Citizens, Dark Hearts, The Yellow Wallpaper, Hack!, Toolbox Murders, Repossessed, Carlo's Wake, Life Among the Cannibals, Ravager, Direct Hit, and a co-starring turn in Henry Jaglom's Going Shopping.
Landau has made television guest appearances, including on Criminal Minds, Millennium, La Femme Nikita, Strong Medicine and a starring role in the Lifetime movie Fatal Reunion. Landau voiced various characters on the animated series Justice League Unlimited and Ben 10 as well as the animated movie Green Lantern: First Flight. She has also voiced characters for three of the BioShock video games.

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